摘要
观察了不同病因胸液中γ干扰素(IFNγ)水平及单个核细胞诱生IFNγ的能力,结果显示结核性胸液中IFNγ水平及单个核细胞产生IFNγ的能力均较其它病因胸液明显增高,而外周血无可测IFNγ,血中单个核细胞对结核菌素纯蛋白衍生物(PPD)刺激产生IFNγ的能力受到抑制。提示结核性胸膜炎的局部细胞免疫功能增强,IFNγ在局部抗分支杆菌感染中起一定作用。胸液中IFNγ测定在结核性胸膜炎与恶性胸液鉴别诊断中有一定参考价值。
FNy levels and IFNy production capability werestudied. The results showed that IFNY levels, IFNYproduction in the tuberculous pleurisy (n=30) were sig-nificantly higher than those in the malignant pleural ef-fusion (n= 23) and the pleural transudate. However,there was no detectable IFNy in the blood, IFNy pro-duction were lower in the blood than in the pleural effu-sion. The finding suggests that IFNy may play an im-portant role in local anti-mycobacterial infection.
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
1995年第2期94-96,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
干扰素类
胸膜积液
结核
免疫
interferon type II Pleural effusionTuberculosis , pleural