胸暖液中免疫岛的意义

The significance of immnune island appeared in pleuraland peritoneal effusion.

巨噬细胞与周围已转化的和未转化的淋巴细胞的堆积团称为免疫岛。观察了１２０例患者的胸腹液涂片，发现５２例（４３．３％）患者的胸腹液中存在免疫岛。在１４例结核性胸腹液中ＩＩ例查见免疫岛，每份涂片面积（２．０ｃｍ×２．５ｃｍ）平均免疫岛数５９．６±１２．８个。在６０例恶性胸腹液中，２９例（４８％）查见免疫岛，每份涂片面积（２．０ｃｍ×２．５ｃｍ）平均免疫岛数３９．２±１８．９个。引起免疫岛的可能机制是病原微生物、肿瘤抗原等异物刺激机体免疫反应的结果。

acrophage surrounded by transformed or untrans-formed lymphocytes is called immune island. Aimmingat this problem, we made a survey of 120 pleural andperitoneal effusion smears with a variety of patients anddiscovered that this island appeared in 52 (43. 3 % ) cas-es. The positive results existed in 11 of 14 (79% ) caseswith tuberculosis and 29 of 60 (48 % ) cases with malig-nant diseases. The average number of island on eachpositive smear (2. ocm × 2. scm) is 59. 6 ± 12. 8 in theformer and 39. 2± 18. 9 in the latter. The mechanism ofthis phenomenon may be due to the response to foreignstimulus from pathogenic and cancer antigen.