摘要
为研究吸入皮质激素倍氯米松对哮喘患合体内嗜酸粒细胞、Ｔ－淋巴细胞功能状态的影响，对治疗前后哮喘患者血清嗜酸性阳离子蛋白（ＥＣＰ）、可溶性白细胞介素－２（ｓＩＬ－２Ｒ）浓度及患者乙酰甲胆碱气道反应性进行检测。结果表明。吸入皮质激素６周后，血清ＥＣＰ、ｓＩＬ－２Ｒ浓度降低，肺功能改善、乙酰甲胆碱－ＰＣ＿（２０）（ＦＥＶ＿１下降２０％时的乙酰甲胆碱激发浓度）值增高。提示：糖皮质激索能抑制嗜酸性粒细胞、Ｔ－淋巴细胞激活。具有抗炎和降低气道高反应性的作用。
o study the influence of corticosteroid and β_2-ago-nist on cosinophil and T lymphocyte functioning state inthe asthmatics,we measured the serum ECP、sIL-2Rlevels and airway reactivity before and after 6-weektreatment with beclometasone and terbutalin.The re-sult revealed that after inhalation of steroid,the serumECP、sIL-2R levels decreased,whereas the lung functionimproved and MCH-PC_(20)values increased.It suggestedthat steroid could inhibit activation of eosinophil and Tlymphocyte as well as show the effect of anti-inflamma-tion and reducing AHR.
出处
《中华结核和呼吸杂志》
CSCD
北大核心
1995年第5期306-308,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
