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环氧化酶-2表达与肿瘤关系的研究进展 被引量:9

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摘要 环氧化酶-2(COX-2)在多种恶性肿瘤中高表达,通过抑制细胞凋亡等机理促进肿瘤的发生和发展。本文综述了COX-2基因结构、生物学特点和在常见恶性肿瘤中的表达及预后的研究进展。
出处 《现代肿瘤医学》 CAS 2005年第4期573-575,共3页 Journal of Modern Oncology
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  • 1Appleby SB, Ristimaki A, Neilson K, et al. Structure of the human cyclooxygenase - 2 gene [ J ]. Biochem J, 1994, 302 ( part 3): 723 - 727.
  • 2Hla T, Neilson K. Human Cyclooxygenase - 2 cDNA [ J ]. Proc Natl Acad Sci USA, 1992, 89:7348 - 7388.
  • 3Wilson KT, Fu S, Ramanujam KS, et al. Increased expression of inducible nitric oxide synthase and cyclooxygenase -2 in Barrett's esophagus and associated adenocarcinomas [ J ]. Cancer Res,1998, 58:2929 ~2934.
  • 4Altorki N. Cox - 2: a target for prevention and treatment of esophageal cancer[ J]. J Surg Res, 2004, 117:114 - 120.
  • 5Murata H, Kawano S, Tsuji M, et al. Cyclooxygenase-2 overexpression enhances lymphatic invasion and metestasis in haman gastric carcinoma [ J]. Am T Grastroenterol, 1999, 94:455 ~ 457.
  • 6Konturek PC, Konturek SJ, Pierzchalski P, et al. Cancerogenesis in Helicobacter pylori infected stomalch - role of growth factors,apoptosis and cyclooxygenases [J]. Med Sci Monit, 2001, 7:1092~ 1107.
  • 7Maekawa M, Sugano K, Sano H, et al. Increased expression of cyclooxygenase- 2 in human colorectal cancers and adenomas, but not in hyperplastic polyps [J]. Jpn J Clin Oncol, 1998, 28(7):421 ~ 425.
  • 8Boolbol SK, Dannenberg A J, Chadburn A, et al. Cyclooxygenase -2 overexpression and tumor formation are blocked by sulindac in a murine of familial adenomatous polyposis [ J ]. Cancer Res,1996, 56 ( 11 ) :2556 ~ 2560.
  • 9Dubois RN, Radhika A, Reddy BS, et al. Increased cyclooxygenase- 2 levels in carcinopen -induced rat colomic tumors [ J ].Gastroenterology, 1996, 110(4):1259~1262.
  • 10Sheehan KM, Sheehan K, Donoghue DP, et al. The relation between cyclooxygenase - 2 expression and colorectal cancer [ J ].JAMA, 1999, 282 (13): 1254 ~ 1257.

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