摘要
目的探讨心理因素对妇科恶性肿瘤病人细胞免疫的影响。方法测定60例妇科恶性肿瘤(宫颈癌50、卵巢癌10)患者的焦虑反应、抑郁反应及其CD3、CD4、CD8、CD4/CD8比值、NK细胞、TNF、IL-2。结果严重抑郁反应患者的CD4/CD8比值、NK细胞、TNF显著低于无抑郁反应或轻度抑郁反应的患者,明显焦虑的患者的IL-2低于无焦虑或轻度焦虑的患者。结论严重心理应激可导致妇科恶性肿瘤患者细胞免疫功能损害。
Objective To study the psychological response effect on the cell immunity in the patients of female genital cancers. Methods The anxiety ,depression and CD3、CD4、CD8、NKc 、TNF、IL-2 in 60 patients with female genital cancer were measured .Results CD4/CD8、NKC reduced in the patients with the serious depression; IL-2 decreased in the patients with the anxiety. Conclusion The study indicts that the serious psychological stress may impact cell immunity in the patients with female genital cancers.
出处
《现代肿瘤医学》
CAS
2005年第4期508-510,共3页
Journal of Modern Oncology
关键词
妇科恶性肿瘤
心理因素
细胞免疫
female genital cancer
psychological stress
cell immunity
