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ZD1839对免疫效应细胞裂解人肺腺癌A549细胞作用的影响

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出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2005年第7期493-495,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
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  • 1Ciardiello F, Caputo R, Bianco R ,et al. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res,2001,7:1459-1465.
  • 2Janmaat ML, Kruyt FA, Rodriguez JA, et al. Response to epidermal growth factor receptor inhibitors in non-small lung cancer cells:limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular singal-regulated kinase or Akt kinase pathways. Clin Cancer Res, 2003,9:2316-2326.
  • 3Sirotnak FM, Zakowski MF, Miller VA ,et al. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res,2000,6:4885-4892.
  • 4Ferry D, Hammond L, Ranson M, et al. Intermittent oral ZD1839 (Iressa), a novel epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), shows evidence of good tolerability and activity. Final results from a phase 1 study. Proc Am Soc Clin Oncol, 2000,19:3a.
  • 5Cohen MH, Williams GA, Sridhara R,et al. FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets. Oncologist, 2003,8:303-306.
  • 6Naruse I, Ohmori T, Ao Y, et al. Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) IRESSA (ZD1839) in an EGFR-expressing multidrug-resistant cell line in vitro and in vivo. Int J Cancer, 2002,98:310-315.

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