紫外线照射充氧自血回输治疗慢性肺心病血液高凝状态的研究

Study of Ultraviolet Blood Irradiation and Oxygenation (UBIO) for Chronic Cor Pulmonale with Blood Hypercoagulability

应用紫外线照射充氧自血回输（ＵＢＩＯ）治疗慢性肺心病血液高凝状态５６例，另以５６例作对照。结果表明，总有效率ＵＢＩＯ组为９３％，对照组为７１％，两组差异有显著性（Ｘ２＝４．３８，Ｐ＜０．０５）．ＵＢＩＯ组凝血时间、红细胞压积、纤维蛋白原定量、纤维蛋白降解产物、抗凝血酶ＩＩＩ异常变化的改善比对照组明显（Ｐ＜０．０５），全血粘度、血浆粘度、红细胞变形和球结膜微循环的血管形态、周围状态及总积分改善非常显著（Ｐ＜０．０１），ＰａＣＯ２下降，ＰａＯ２，ＳａＯ２上升非常显著（Ｐ＜０．０１～０．００１），对照组改善不明显（Ｐ＞０．０５）．

cases of chronic ocr pulmonale with blood hypercoagulability were treated with UBIO and another 56 cases were as a control group. The result showed that the total effective rate of the UBIO group was 93%, but that of the control group was 71%. There was a significant difference (P < 0. 05 ). In UBIO group, the time of blood coagulation, hematocrit, fibrinogen, fibrinogen degradation products and antithrombin-III were markedly improved as compared with the control group (P<0. 05). At pre-and posttreatment with UBIO, there was a significant difference in whole blood viscosity, plasma viscosity, RBC deformity rate and microvasculature morphology in bulbar conjunctva and so on. At the same time, the decrease of PaCO2 and raise of PaO2, SaO2 were also better than those of control group (P<0. 01～0. 001).