济南市新生儿乙型肝炎疫苗免疫预防的成本－效益分析

Cost-benefit Analysis on Immunization of Newborns with Hepatitls B Vaccine in Jinan City

运用决策树模型及成本－效益分析方法。对济南市新生儿乙型肝炎疫苗免疫预防的接种策略及经济效益进行了决策分析，结果显示，不同剂量的三种接种策略均可获得正效益，其效益一成本比值为４２．４１～４８．０１，从卫生经济学角度看，三种接种策略均是可行的，经决策分析认为，在疫苗紧张的情况下，应将重点放在母婴阻断上，若疫苗供应允许，则应对全体新生儿进行免疫。另外，敏感性分析结果显示，济南市实施新生儿乙型肝炎疫苗免疫预防其经济效益是非常显著的，也是极其稳定的。

The decision tree model cost-benefit analysis method was,used to analyse the strategies and economicbenefits of immunization of newborns with hepatitis B vaccine,in Jinan City. The results showed that all thethree vaccination strategies could all produce positive benefits. Their BCR were 42.41 to 48.01. Through thedecision analysis,it concluded that stress should be laid on the blocking of mother-to- infant transmission,andthat if there are sufficient HB vaccines,all newborns should be vaccinated .In addition, the results of sensitivi-ty analysis indicate that the benefits of HB vaccination are outstanding and quite, stable.