硬膜外腔持续滴注复合液治疗晚期癌痛的观察

Treating cancer pain by continuous epidural drip with the compound medicine solution

１２４例晚期癌痛患者随机分为复合液组７６例和单纯吗啡组４８例。复合液组选择低浓度局 麻药复合少量吗啡及激素、Ｂ族维生素，有镇痛效果确切，吗啡用量小，副作用少等优点。单纯吗啡组虽 能达到良好镇痛效果，但需逐渐加大用药量，且副作用多。两组比较有显著差异（Ｐ＜０．００１）。硬膜外腔 滴注复合液较单纯推注吗啡优越。

one hundred and twenty four patients suffering from advanced cancer pain were randomly divided into group I (n = 76) receiving continuous epidural drip with the compound medicine solution and group I (n = 48) having sim- gle morphine injected epidllrally. The compound medicine solution consisted of low concentrations of local anesthet ics,small dose of morphine,dexamethasone and vitamin B complex. The results showed that a definite analgesicef- feet , less morphine dosage and fewer side effects were observed in group I,good analgesic effect was produced' in group ,but morphine dose had to be increased as time went on and more side effcts occured,in which the 'tiffer ences were significant (P<0. 001 )between two groups. It,s suggested that continuous epidural infusion of this corn pound medicine solution has superior effects to epidural single morphine.