非神经源性逼尿肌膀胱颈协同失调

Non-neurogenic detrusor-bladder neck dyssynergia

报告５例原发性膀胱颈功能障碍患者表现为排尿时膀胱颈开放不良，病变为逼尿肌膀胱颈协同失调，可命名为非神经源性逼尿肌膀胱颈协同失调。提出其诊断标准：（１）有下尿路功能性梗阻；（２）排尿时膀胱颈开放不良，膀胱内压－膀胱颈内压梯度异常；（３）无影响膀胱尿道功能的神经系疾患。同时对此症的发病机理和治疗选择进行了讨论。

Five patients with primary dysfunction of the bladder neck were presented. In these patients bladder neck could not be funneled adequately during voiding, which implies detrusor-bladder neck dyssynergia. We consider the condition as non-neurogenic detrusor-bladder neck dyssynergia (NNDBND).The criteria for its diagnosis are:(1) obstructive symptoms of the lower urinary tract caused by functional disturbance;(2) abnormal bladder neck funneling during voiding and excessive pressure gradients across the bladder neck;(3)without neurogenic cause accounting for the functional disturbance ofthe lower urinary tract.The pathogenesis and treatmentof NNDBND were discussed.