摘要
应用S-P免疫组织化学方法对53例膀胱肿瘤中抑癌基因P16进行了研究。结果显示:49例膀胱移行细胞癌P16表达的阳性率为44.90%,其阳性率在肿瘤的病理分级、临床分期及预后等方面差异有显著性(P<0.05)。提示P16在抑制膀胱肿瘤的发生、发展中起重要作用。
cases of bladder carcinoma were studied by S-P immunohistocheminal technique(IHC).The results showed that the positive rates of P16 were 44.90% in 49 cases of bladder transitional cell carcinoma,their positive rates being significantly different with different pathological grading,clinical staging and prognosis 1111of the carcinoma(P<0.05).It suggests that P16played an important role in suppressing the genesis and the develepment of bladder carcinoma.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1995年第12期722-724,共3页
Chinese Journal of Urology
关键词
膀胱肿瘤
癌
基因
免疫组织化学
Bladder neoplasmas Carcinoma Gene Immunohistochemistry