^（131）碘过氯酸钾加碘释放试验的临床评价

CLINICAL EVALUATION OF IODINE ATTACH IN^(131) I-POTASSIUM PERCHLORATE DISCHARGE TEST───AREPORTOF200 CASES

常规的￣（１３１）碘过氯酸钾释放试验（简称￣（１３１）Ⅰ释放试验）对酪氨酸碘化障碍的甲状腺疾病诊断有一定的价值，但诊断率较低。采用加碘的方法进行￣（１３１）碘释放试验（简称￣（１３１）Ⅰ加Ⅰ释放试验），发现诊断率明显提高。１６０例甲状腺疾病患者中１１０例慢性淋巴细胞性甲状腺炎的￣（１３１）Ⅰ释放试验和￣（１３１）Ⅰ加Ⅰ释放试验的各时相阳性率比较，差异有非常显著性（Ｐ＜０．００１）；前者３０分钟、１小时、２～３小时释放阳性的例数和百分率依次为９例（０．０８２）、１９例（０．１７３）、３６例（０．３２７），而后者为７４例（０．６７３）、８９例（０．８０９）、９３例（０．８４５）。５０例其他甲状腺疾病的￣（１３１）Ⅰ加Ⅰ释放试验的释放率亦较正常人高，说明在这些疾病中也有不同程度的碘有机化障碍。￣（１３１）Ⅰ加Ⅰ释放试验也对这些病变功能状态的判断与其病理改变符合。

The diagnostic rate of routine￣ (131)I-potassium perchlorate discharge test,￣(131) I discharge test for short, is low in thyroid diseasesof tyrosine iodization disorder. This paper studied the method of iodine attach in￣(132)I discharge test.It was then observed that thediagnostic rate rose obviously. In 110 patients of chronic lymphocytic thyroiditis out of 160 patients with thyroid diseases,the num-ber of positive cases and percentage at 30 minutes,1 hour,2～3 hours were respectively 9(0.08),19(0. 173)and 36(0.327)detected by ￣(131)I discharge test,as compared with 74(0. 673),89 (0.809)and 93(0. 845)detected by iodine attach in ￣(131)I dis-charge test.The discharge rate of iodine attach in ￣(131)I discharge test was raised too in 50 other patients of thyroid disease as com-pared with normal volunteers.This fact indicates that the iodization disordor exists to various extent in these diseases. Iodine attachin ￣(131)I discharge test had results that accord with the functional status and pathological changes of these diseases.