症状性骨关节炎的临床和流行病学探讨

OSTEOARTHRITIS:CLINICAL AND EPIDEMIOLOGICAL INVESTIGATION

对澄海市１７２２名成人的调查结果示骨关节炎（ＯＡ）患病率为８．３％，且其男女差异不大。ＯＡ的患病率４０岁以后明显升高，５０～５５岁达高峰。流行病学发现和５０３例就诊ＯＡ病人所见，骨质疏松（ＯＰ）的发生率为３０％左右，以女性多见，尤以绝经后妇女明显升高。６６例腰椎ＯＡ的ＣＴ检查结果示８９．４％（５９例）伴有椎间盘膨出、突出或脱出，以腰。＿（４／５）发生率最高。对１０例２０个膝关节行核磁共振检查发现，所有Ｘ线有改变的ＯＡ病例均伴有软骨变性、半月板变性／损伤、滑囊炎、滑膜炎以及韧带病变等之一项以上或同时存在多种病变。作者认为，ＯＡ是一种异质性疾病，其治疗应注意高度个体化。

population study of 1 7 2 2 adults in Chenghai city,Guangdong province showed that the prevalence of osteoarthritis(OA ) was 8.3%and there was no significant difference between male and female. The prevalence of OA increased after the age of 40 and reached a peak at 50～55 years. The prevalence of os-teoporosis(OP)in OA patients of this population survey and in patients in our clinic was around 30%,OA accompanying OP was rnore frequently seen in female than male, especially in postmenopausal women.The results of CT screen of lumbar spine in 66 OA patients showed:89.4%(59 cases) was assOciated with the protrusion of intervertebrale disc,occurring frequently at L_4 and L_s.MR imaging of 20 knee joints in 10 cases of OA paitents with knee involvement showed:all of the patients were associated with one or all of he following conditions:chondropathies,degeneration or injury of semilunar plate , bursitis and synovitis.It is suggested that OA is a heterogeneous disorder and must be treated with different ways.