小儿睾丸内胚窦瘤九例报告

Endodermal sinus tumor of testis in children: reportof 9 cases

作者报告９例小儿睾丸内胚窦瘤。患儿年龄７个月～５岁。９例均行经腹股沟根治性患侧睾丸切除术，１例腹膜后转移者加作腹膜后肿块探查活检。４例术后进行了不规则化疗。术后随访１．５～７年，尚健存者５例，均为临床Ⅰ期患者；另４例随访期间死于肿瘤转移。由于内胚窦瘤有合成甲胎蛋白（ＡＦＰ）的生物学特性，所以测定血清ＡＦＰ水平对确定肿瘤性质、监视治疗效果有重要意义。作者主张对临床Ⅰ期患者行睾丸切除术加短期化疗，不必常规进行腹膜后淋巴结清除手术。

AbstractNine Children with endodermal sinus tumor oftestis have been treated since 1982.Their age rangedfrom 7 months to 5 years. Radical inguinal orchiecto-my was carried out in all the patients. Four patientshave received irregular chemotherapy. The follow-upshowed that 4 died of the metastasis within 5 years and5(stage Ⅰ clinically)survived without evidence of therecurrence for 1.5～7 years after operation. SerumAFP determination may give important information forthe classmcation of the tumor and the evaluation of thefollow-up results, For the cases of clinical stage Ⅰ,radical orchiectomy, short course of chemotherapy,and frequent observations of AFP level are advocated.