小儿急性肾功能衰竭100例临床分析

CLINICAL ANALYSIS OF 100 CASES OFACUTE RENAL FAILURE IN CHILDREN

介绍１００例小儿急性肾功能衰竭（ＡＲＦ）的病因、临床表现、实验室检查、病理及预后。肾前性１３例（１３％），肾性８６例（８６％），其中肾小球疾病６６例（６６％），肾后性１例（１％）。３１例肾活检，病理为９种类型，毛细血管内增生性肾小球肾炎（ＥｎＰＧＮ）８例（２５．８１％），系膜增殖性肾小球肾炎（ＭｓＰＧＮ）４例（１２．９０％），膜增殖性肾小球肾炎（ＭＰＧＮ）１型５例（１６．１３％），局灶节段性肾小球硬化（ＦＳＧＳ）３例（９．６８％），增生性硬化世肾小球肾炎（ＰＳＧＮ）５例（１６．１３％）。本文强调了小儿肾活检的临床意义及对预后的分析。

he pathogeny, symptorn, results of laboratorycheck, pathology and prognosis of 100 cases of acuterenal failure (ARF) in children with treating in our de-partment from year of 1981 to December of year of1993 are introduced. The cases of prior kidney ARFwere 13% of all the cases (13 cases) and the cases ofinner kidney ARF were 86% of all the sick children(86 cases)while the cases of post kidney ARF were 1%of the all (1 case). The cases of the damage of glomeru-lus of kidney were 66% of all the inner kidney ARF( 66 cases ) . Among the 31 cases of renal biopsy , 9 kindsof pathological pattern existed. The cases of endocapil-lary proliferative glomerulonephritis (EnPGN) were 8cases (25. 81%). The cases of mesangioproliferativeglomerulonephritis (MsPGN) were 4 cases (12. 90% ). The cases of type-1 membranoproliferative glomeru-lonephritis (MPGN-1) were 5 cases (16. 13%) . Thecases of focal segmental glomerulosclerosis (FSGS)were 3 cases (9. 68% ) . The cases of proliferate scleros-ing glomerulonephritis (PSGN) werw 5 cases(16. 13 %) . The article emphasizes the clinical signifi-cance of renal biopsy and the analysis to the prognosisin ARF of children.