摘要
对肾综合征出血热(HFRS)病毒的微量细胞培养法和空斑法进行了比较。4株HFRS病毒及3株特异性McAb的测定结果表明,微量细胞培养法测得的病毒滴度高于空斑法,但后者检测McAb的中和效价却高于前者。
Comparison of the micro cell culture test and the plaque assay was carried out by measuring titer of 4 strains of HFRS virus and detecting 3 neutralizing McAbs against HFRS virus. It showed that the virus titers measured by the micro cell culture test was higher than that measured by plaqus assay, but the titers of neutralizing McAb detected by the plaque reduction neutralization test was much higher than that detected by the micro cell culture test. The above result was discussed and it was thought that each of the two tests had its own advantage in practical use.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1995年第2期126-128,共3页
Chinese Journal of Experimental and Clinical Virology
关键词
肾病综合征
出血热病毒
微量细胞培养法
空斑法
Hemorrhagic fever with renal syndrome virus
Micro cell culture test
Plaque assay
Monoclonal antibodies