扩大壁细胞迷走神经切断术对患者远期营养及消化功能影响的研究

Long-term effect of extended parietal cell vagotomy onpatients′nutrition and digestive function

作者报道了３６例扩大壁细胞迷走神经切断术（ＥＰＣＶ）与３０例胃大部切除术后７～１４年的患者营养及消化功能的对比研究。对两组患者术后营养状况、胃分泌功能、胃肠运动功能和小肠消化吸收功能进行评价。结果显示：胃大部切除组术后患者状况欠佳，贫血为３３．３％，体重减轻为５４％，而ＥＰＣＶ组术后患者营养状况良好，未发生贫血者，体重比术前增加３公斤者占５６％，在生活质量上明显优于胃大部切除组。其最重要的原因与保存了胃与幽门和胃的正常排空功能有关。研究结果表明，ＥＰＣＶ能够维持生理浓度的胃酸和正常的消化及吸收功能，其对患者术后远期营养及消化功能的影响较胃大部切除术小。这为ＥＰＣＶ手术的合理性提供了可靠的理论根据。

AbstractIn this study,36 patients undergoing extendedparietal cell vagotomy (EPCV) were compared with 30patients with subtotal gastrectomy 7～14 years aftersurgery. The patients′nutritional status,gastric sec-tretion, gastrointestinal motility and intestinal absorp-tion function were evaluated.The nutritional status wasgenerally less satisfactory in 33.3% patients withanaemia after gastrectomy and decrease of body weightin 54%. The patients after EPCV were all in good nu-tritional status,with no anemia; 56%of them had abody weight increase of more than 3kg. Therefore,therationality of EPCV was estalished.