大肠癌肝转移的临床病理学特点及临床意义

Clinical and pathological analysis of patients with hep-atic metastases from colorectal cancer

作者对手术切除大肠癌合并肝转移癌的３４例（转移组）及无肝转移大肠癌的４０例（对照组）的资料，依据日本“临床·病理大肠癌处理规约”进行了临床病理学对比分析。结果表明淋巴结转移（Ｎ）、远处转移（Ｐ）各转移因子的分级转移组明显高于对照组（Ｐ＜０．０１）；浆膜浸润（Ｓ）、静脉浸润（Ｖ）、淋巴管浸润（Ｌ）各浸润因子分级转移组亦明显高于对照组（Ｐ＜０．０１）；转移组浸润方式ｉｎｆγ占７９．４％，两组间差异极显著（Ｐ＜０．０１）；癌原发部位转移组多见乙状结肠（４１．９％），对照组则多见右半结肠（５５％），两组间差异极显著（Ｐ＜０．０１）；组织学分型两组间差异显著（Ｐ＜０．０５）；肉眼分型及肿瘤最大直径面积两组间则无显著差异（Ｐ＞０．０５）。依据本组结果作者提出了术中彻底切除转移癌灶，应用术中实时Ｂ超的临床病理学指标及术后癌肝转移的半定量预测方法并应用模糊术学原理绘出预测曲线。

Abstract74 patients with colorectal cancer were divided intogroup A(34)with liver rnetastasis and group B(40)withOut by retrospective analysis. Based on the“Japanese General Rules for Clinical and PathologicalStudies on Cancer of Colon,Rectum and Anus”,the in-dicators of clinicopathologicaI S,N,P,V,L,and infwere significantly different between the 2 groups(P<0.01).But tumor size showed no significant differencebetween the 2 groups(P>0.05);In the group A, cas-es of poorly differentiated carcinoma and medullarytype carcinoma were more than those in the group B(P<0.01).