摘要
为了研究肝炎后肝硬化与肠道菌群间的关系，对４６名肝炎后肝硬化患者和５２名健康对照者进行了对比研究。方法为取０．５克新鲜粪便，用稀释液按１０倍稀释法将粪便稀释至１０－８，然后用滴注法接种于选择性培养基。选择肠道菌群中具代表性的需氧菌和厌氧菌共１０种。结果示：（１）实验组的肠杆菌、葡萄球菌、酵母菌、拟杆菌和双歧杆菌量明显低于对照组（Ｐ＜０．０１）。（２）伴腹泻者真杆菌减少，梭菌增加（Ｐ＜０．０５）。结果表明，肝硬化患者均有不同程度的肠菌群失调，而失调的程度往往与肝功能损害程度有关。
n order to study the relationship between changes of posthepatic cirrhosis and
intestinalmicroflora, 46 cirrhotic patients were studied with 52 healthy adults as control.
Methods :Fresh fecal specimens(0.5g) were diluted serially in a decimal way to l0-8 and then
inoculatedinto l0 selective culture media and selected l0 of them as representive
intestinalmicroorganisms. Results:(1)The numbers of enterobacteria, staphylococci, bacteroids
andbifidobacteria, were significantly less than those in controls (P<
0.01).(2)Enterobacteriadecreased and fusiformis increased in patients with diarrhea. These
results showed that therewere varying degrees of changes of intestinal microflora in patients
with posthepatic cirrhsis.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1995年第2期75-77,共3页
Chinese Journal of Digestion
关键词
肠道
菌群
肝硬变
肝炎
Cirrhosis
Microflora: Intestine. Cronkhite.
