摘要
对３５例尿道下裂小儿及２０例正常儿作黄体素释放激素（ＬＨ－ＲＨ）兴奋试验和人绒毛膜促性腺激素（ＨＣＧ）试验，应用放射免疫法测定了血清黄体素（ＬＨ）、卵泡刺激素（ＦＳＨ）、及睾酮（Ｔ）浓度。检查结果发现，尿道下裂患儿ＬＨ－ＲＨ刺激后的血清ＬＨ、ＦＳＨ浓度高于正常对照组，而注射ＨＣＧ３天后的血清Ｔ浓度较正常对照组低下。
In order to explore the endocrine abnormalities in prepubertal boys with hypospadias, LH-RH stimulating test and/or HCG test were performed on 35 prepubertal boys with hypospadias and 20 comparable normal controls,whose ages ranged from 2 to 9 years. Serum concentration of luteinizing hormone, follicle-stimulating hormone and testosterone were determined by radioimmunoassay.The levels of serum luteinizing hormone and follicle-stimulating hormone in patients after the stimulation of LH-RH were significantly high than those in controls. The level of serum testosterone after 3 day's treatment of HCG in patients was statistically lower than that in controls. The endocrine abnormalities and their possible etiological effect in pypospadias were discussed in this article.
出处
《中华小儿外科杂志》
CSCD
1995年第3期138-140,共3页
Chinese Journal of Pediatric Surgery
