摘要
分析43例超重者(体重指数>25kg/m2)经8周减重后血压、血脂、血糖及尿酸的变化情况表明:收缩压和舒张压分别平均下降0.44和0.43kPa(3.3和3.2mmHg)(P值均<0.05)。血清总胆固醇、甘油三酯分别平均下降0.338mmol/L和0.407mmol/L(P值均<0.01);低密度脂蛋白胆固醇平均下降0.138mmol/L但未达统计学显著水平;高密度脂蛋白胆固醇和低密度脂蛋白胆固醇比值未见明显变化。血清尿酸平均下降41.65μmol/L(约13%,P<0.001)。血糖无明显变化。说明本组超重者不仅体重得到了控制,而且血压、血脂模式和血尿酸等均发生了有利于心血管病预防的转变。
Abstract Objective:To observe the effect of weight loss program on blood pressure,serum lipids,serum uric acid and plasma glucose.Subjects:43 overweight (BMI> 25 kg/m2) men and women.Methods:Before and after 8 weeks dietary adjustment for weight foss, a 12-hour fasting sample was drawn and blood pressure recorded. Serum lipids (including TC, TG and HDL-C),glucose and uric acid were measured then.Results: On average, SBP and DBP decreased by 3.3and 3.2 mmHg respectively (both P<0. 053 ), TC and TG by 13. 0 and 36. 0 mg/dl respectively (both P<0. 01), TC/HDL-C by 0- 3 (P<0.05) , LDL-C decreased by 5. 3 mg/dl but not statisticaly significant;HDL-C, HDL-C/LDL-C ratio and glucose changed insignificantly.Uric acid decreased significantly by 0.7mg/dl (about 13% ) .Conclusion:Weight loss program,based on dietary adjustment,can not only reduce weight,but also make favorable changes in blood pressure,serum lipids profile and uric acid in terms of prevention of cardiovascular diseases.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
1995年第4期299-301,共3页
Chinese Journal of Cardiology