摘要
在236例自身免疫性溶血性贫血(AIHA)患者中检出Evan's综合征47例,占同期AIHA发病率的19.9%。免疫分型以IgG+C_3型最多,C_3型较IgG型偏多。对30例随访复查发现。经药物及手术治疗后,大部分患者Hb及BPC均有明显上升,其Hb上升的程度均优于血小板上升的程度,且较稳定。Hb上升的速度先于抗体或补体下降的速度。免疫分型也可发生改变。
mong 236 patients with auto immune hemolytic ane-mia (AIHA) , 47 (19. 9 %) were diagnosed as Evans syn-drome. Immunoclassifying results showed that the fre-quency order was IgG + C_3>C_3>IgG subtype. The re-sults of follow-up in 30 patients showed that the levels ofHb and platelet were sigificantly elevated after treatmentwith drugs or splenectomy in most of cases. The increaseof Hb was greater and more stable than that of platelet ,and the increase of Hb is more rapid than the decrease ofantibodies or coniplement. After treatment, the im-munosubtype conversion might occur in some cases.
出处
《中华血液学杂志》
CAS
CSCD
北大核心
1995年第3期132-133,共2页
Chinese Journal of Hematology
关键词
埃文斯综合征
免疫分型
脾切除
药物疗法
Evans syndrome Laboratory indexImmunoclassification Therapeu-tic effect of drugs or splenectomy