眼内骨化

INTRAOCULAR OSSIFICATION

对因内眼疾病而摘除的１０８３只眼球病理切片进行复习，发现眼内骨化３０例，占２．７７％。与骨化有关的眼部病变包括眼外伤、眼内炎、恶性肿瘤、血管瘤、Ｃｏａｔｓ病和先天性小眼球。病程最长４９年，最短３４天。骨化部位有晶体、睫状膜、玻璃体、视网膜及脉络膜。在萎缩的眼球内，病程越长，发生骨化的可能性越大。眼内骨化应与眼内钙化及脉络膜骨瘤相区别。

Thirty eyes(2.77%)with intraocular ossification were found in reviewing pathologic sections of 1083 eyes enucleated owing to the different intraocular disease from 1949 to 1993.The primary ocular diseases inducing intraocular ossification included trauma,endophthalmitis,malignant tumor,hemangioma,Coats’disease and congenital microphthalmus。The time interval between the insult and enucleation varied from 34 days to 49 years。The sites of ossification were found in crys-talline lens,cyclitic membranes,vitreous,choroid and retina,and either singular or multiple in num-ber,Intraocular ossification is a common pathological manifesation in phthisis bulbi,but rarely pre-sent in ocular malignant tumor.The longer the course of disease is,the more frequent the ossifica-tion can occur。Intraocular calcmcation arid choroidal osteoma should usually be considered in differ-ential diagnosis。