儿童空肠弯曲菌感染的流行病学研究

Epidemiological Investigation of Campylobacter Jejuni Infection in Children

用２年时间对成都市儿童空肠弯曲菌感染进行了流行病学调查研究。１０９２例小儿急性腹泻中空肠弯曲菌检出率为１１．３６％，１～２岁检出率最高，６个月以内婴儿检出率最低。小儿急性腹泻全年均可检出空肠弯曲菌，以春夏季检出率较高，秋冬季较低。幼儿园健康儿童空肠弯曲菌带菌率为５．０９％，各幼儿园存在差异有显著性，分析其原因可能与儿童的家庭居住情况不同有关。耐药谱结合质粒分析应用于托幼机构儿童空肠弯曲菌感染调查，结果提示：儿童空肠弯曲菌感染可能是由许多在遗传学上同源相关性较远的空肠弯曲菌所引起。

pidemiological studies on carnpylobacter jejuni infection in children were carried out in Chengdu during Decetnber 1987 to October 1989. Detection rate of campylobacter in 1092 children with diarrhea was 11.36%,with the highest in children aged 1-2 and the lowest in babies within six months, Campy-lobacter jejuni could be detected in young children with acute diarrhea all the year round, with a higher detection rate in the spring and summer and lower in the autumn and winter. Campylobacter jejuni could be detected in 5,09% of healthy children,with a significant difference between kindergartens due to their living conditions. Use of spectrum of drug-resistance and plasmid analysis in children of nurseries and kindergartens to study campylobacter infection suggested campylobacter jejuni infection in children could be caused by a lot of distant-associated strains with genetic homogeneity.