摘要
我们将 Burke 的方法加以改进,制作出了戊二醛胶原人工皮,经动物实验测定丁蒸发量、粘附力及抑菌作用,证明其透气性能好,粘附力强,具有抑菌作用,可减少水分蒸发和蛋白质电解质的丢失,且无排异反应,是一种理想的人工皮。我们还将其应用于临床30例病人创面,其创面愈合时间为24±3天,对绿脓杆菌感染及慢性溃疡病人的创面效果尤佳。值得推广。
The glutaraldehyde cross-linked collagen artificial skin was made with the modified Burke's method.It is an ideal artificial skin in that animal tests proved that it has the effect of bacteriostasis with strong adhesiveness and good porosity,is capable of decreasing vaporization and the loss of protein and electrolyte,and without rejection reaction.Clinical use of the artificial skin in 30 patients resulted in an average heading time of 24±3 days of the eschar-excised wound covered with the artificial skin and auto- graft of skin seeds.It is especially effective in Pseudomonas aeruginosa infected wound and chronic ulcer.
关键词
戊二醛
胶原
人工皮
Glutaraldehyde
Artificial skin
Burn
