摘要
报道3个剂量滋肾通脉中药安脂舒粉治疗性给药7d,对食饵性高脂血症大鼠血脂和肝脏脂质的影响。结果表明安脂舒粉能明显降低高TC血症大鼠血中TC和AI水平,降低肝脏TC和TG的含量,对血液粘度和红细胞聚集指数有降低趋势。其调脂机理与影响外源性脂质代谢和肝脏脂质代谢有关。
The effect of Anzhishu Powder (AP) on dietetic hyperlipidemia in rats was studied. APwas given orally at the dosages of 32g/kg, 24g/kg and 18g/kg respectively for 7 days and clofibrate at a dailydosage of 480mg/kg as compared. It was found that the AP reduced markedly the plasnia level of totalcholesterol (TC), the atherosclerosis index (AI, TC-HDL-C/HDL-C) and liver TC and TG levels. Themechanism of AP for lipid regulation may be related to its influence on exogenous lipid metabolism andliver lipid metabolism .
出处
《中药新药与临床药理》
CAS
CSCD
1995年第2期26-27,共2页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
安脂舒粉
药理学
高脂血压
中医药疗法
Anzhishu Powderlpharmacology,hyperl ipidemiajdrug effects,blood viscosityldrug effects,lipidslblood