Ⅲ期乳腺癌综合治疗方案初探

Preliminary study on combined treatment of stage Ⅲ breast carcinoma

本院自１９７６～１９８９年收治Ⅲ期乳癌１７６例，全组５年生存率，局部复发率，远处转移率分别为５０％、１２．５％、２１．５％。单纯手术组（３０例）分别为４３．３％、２６．７％、４０％；术后放疗组（４９例）分别为５１％、８．２％、３６．７％；术后化疗组（３０例）分别为５０％、１６．７％、１０％；术后放、化疗组分别为５２．２４％、７．５％、７．５％。局部复发率单纯手术组最高，术后放疗及放化组最低，二者比较有显著性（Ｐ＜０．０５）；远处转移率单纯手术组最高，术后化疗组及放化组最低，（Ｐ＜０．０５）５年生存率综合治疗组较高，但与手术组比较无显著性差别（Ｐ＞０．０５）。

From 1976 to 1989,176 patients with stage Ⅲ breast carcinoma were treated in our hospital.There 5-year survival rate local recarerance rate,the incidence of distant metastases were 50%,12.5%,21.5%;the rates of operation alone(30 cases)were 43.3%,26.7%,40%;The ratesof operation plus chemotherapy(30 cases) were 50%,16.7%,10%;The rates of operation plusradiotherapy(49 cases)were 51 %,8.2%,36.7% ;The rates of operation plus radiotherapy,andcheuo therapy were 52.24%,7.5 %.7.5%;The local recarerance rate of the operation alone wasthe greatest.But the operation Plus radiothrapy and chemotherapy was the lowest.The differencebetween two groups was significant(P<0.05),The distant metastasis rate of the operation alonewas the greatest among the groups.the operation radiotherapy and chemotherapy were the lowest(P<0.05). 5-year survival rate of combined treatment was great. but there was no significantdifference between the combined treatment and the operation (P>0. 05).