双途径介入治疗晚期肺癌

Two Route Interventional Chemotherapy in the Treatment of Later Lung Cancer

我们自１９９０年至１９９３年，对８７例晚期肺癌患者采用支气管动脉及肺动脉双途径介入化疗，收到满意疗效。术后平均生存１８个月。与此同期单纯支气管动脉介入２００例，术后平均生存１０．５个月，经过双途径介入化疗大部分病人临床症状缓解，提高了生活质量，部分病人重新获得了手术机会，生存期较单纯支气管动脉介入明显延长。表明肺动脉与支气管动脉同时介入，较单纯支气管动脉介入化疗疗效好，可以互相弥补其不足，更广泛地杀死癌细胞。是一种有效的姑息治疗手段。

cases of later lung cancer were treated by Two Route arterial Chemotherapy (TRAC) viabronchial artery and pulmonary artery. They were all stage Ⅲ-Ⅳ cases (TNM stages) in thisgroup. Selective bronchial arteriography showed the tumer's nourishing blood vessels. TRIC wasperformed injection the bronchial artery with CBP 300mg, ADM 30mg and VP-16 300mg; followed injection the pulmonary artery with VCR ling and MMC 4mg, 5-Fu 500mg etc for ten days. Goood results were achieved CR 90. 87 % of cases; PR55.17%; MR 35. 63% ;NC 5. 7%,PD3. 4 %. TRAC was an effective palliative treatment way in later lung cancer.