煤沥青烟气对职业接触人群姐妹染色单体交换的影响

SCE Effect of Pitch Fume on Occupational Exposed People

利用姐妹染色单体交换率(SCE)的增加与否,作为细胞遗传毒理学的指标来评价一些理化因子的诱变性,是检测化学致突变的方法之一。通过对某碳素厂接触生产性煤焦沥青烟气的工人人体外周血淋巴细胞SCE观察表明,车间接触组工人SCE明显高于非接触组工人(约1.67倍);在接触组中,吸烟者SCE高于非吸烟者;同为吸烟者,接触组工人SCE高于非接触组工人(约1.48倍)。结果提示煤焦沥青烟尘能引起工人SCE的改变。

Using either increased or not of sister chromatid exchange as an index of genetical toxicology to evaluate mutation of physical and chemical factors, it can be used as one of the method for determination of chemical mutagen. Through observation of SCE of exposed people in certain carbon black factory, it showed that: the SCE of exposed people was obviously higher than non-exposed people (about 1.67-fold). Among the group of exposed people, the SCE of cigarette smoking people was higher than that of non-smoking one.