人胚肺细胞转化试验及其对甲基丙烯酸环氧丙酯致癌性的研究

Human Embryonic Lung Cell Transformation Assay and the Carcinogenecity Research of Glycidyl Methacrylate by Using It

建立了人胚肺细胞（２ＢＳ）转化系统，并对甲基丙烯酸环氧丙酯（ＧＭＡ）的潜在致癌性进行了研究。结果表明，转化试验结果良好，试验方法可行。利用２ＢＳ细胞检测ＧＭＡ的转化能力，再次证明了ＧＭＡ对细胞有很强的致转化作用。

A neoplastic transformation assay with human embryonic lung cell(2BS)was established and the potential carcinogenecity of Glycidyl Methacrylate(GMA) was studied.The results showed that a good response of transformation was obtained and the method was feasible.GMA was tested for neoplastic transformation activity using 2BS cells in vitro.The results demonstrated again that GMA had strong effect of transformation to the target cells.