根据损伤组织中C─反应蛋白的含量及分布推断损伤时间

DETERMINATION OF WOUND AGEING BY THE CONTENT AND DISTRIBUTION OF CRP IN SKIN INCISION

作者应用酶联免疫吸附分析和免疫组织化学方法，检测大鼠切创创缘C-反应蛋白含量及分布的变化，探讨它们与损伤时间的关系及其来源。结果表明通过检测损伤组织中C-反应蛋白的含量及分布可推断伤后30分钟至5小时内的损伤时间，并证明C-反应蛋白可由肝细胞合成，组织损伤可诱发肝细胞合成C-反应蛋白。

Depoment of Forensic Medicine Sun Yat-sea University of Medical Sciences Guangzhou 510089The methods of ELISA and immunohistochemistry were used to detect the CRP level and distrbution in the edge of incised wound of rats. The results has showedthat it can be used to estimate the time of injury inflicted 30min to 5h be fore death with the two metheds. The experiment has com-firmed that the CRP may be synthesized by hepatocytes.