6Warren S, Gates O. Multiple primary malignant tumors. A survey of the Literature and a statistical study [J]. Am J Cancer, 1932,16 : 1358.
7Lee TK, Barringer M, Myers RT, et al. Muhiple primary car- cinomas of the colon and associated extracolonic primary malignant tumors[J]. Ann Surg, 1982,195:501.
8Mukesh Verma, Methods in Molecular Biology, Cancer Epi- demiology[M].1(471 ). New York : Humana Press, 2009 : 3 -12.
9Nagy R, Sweet K, Eng C. Highly penetrant hereditary cancer syndromes[J]. Oncogene ,2004,23 ( 38 ) :6445.
10Slattery ML, Levin TR, Ma K, et al. Family history and color-ectal cancer:predictors of risk[J]. Cancer Cause Control, 2003,14:879.
