肝动脉及外周静脉注射阿霉素的血药浓度变化观察

Observation on the changes of Blood Drug Concentration from Injection of Adriamycin through Hepatic Artery and Peripheral Vein

作者采用经肝动脉及外周静脉注射阿霉素的化疗方法，对给药后的血药浓度变化进行对照研究，发现经肝动脉注射后各时刻的血药浓度均明显低于外周静脉给药组，表明经肝动脉给药确实可以减轻化疗的全身毒性反应并提高疗效。

BY injection through hepatic artery and peripheral vein with adriamycin,we have studied thechanges of blood drug concentration compartatively. After injection we found that the blood drug concentrationfrom injection of hepatic artery was evidently lower than that from injection of peripheral vein. The resultsshowed that the systemic toxic responses due to chemotherapy can be relieved and the chemotherapeutic efficacycan be improved by injection through hepatic artery with chemicals.