摘要
自1992年3月治疗非小细胞肺癌48例,其中放热化26例、单纯放疗22例;鳞癌39例、腺癌8例、类癌1例。采用高能X线常规放疗,DT50~70Gy;使用8MHzRF热疗机,放疗后30~60min内热疗,每次60min,温度41~43℃,每周两次、8~12次为一疗程;化疗在放疗后、热疗前或与热疗同时进行,每周1次。治疗结果:放热化组CR6例、PR13例、MR7例;单放组CR4例、PR9例、MR8例、NR1例。总有效率(CR+PR):放热化组73.1%、单放组59.1%,P>0.05。放热化组有5例CT示较大的肿瘤内有明显的低密度区,为肿瘤凝固性坏死征象。与热疗有关的反应为胸痛、心悸和轻度呼吸困难.
The combination therapy of lung cancer with
radiation-hyperthermia and chemotherapywas investigated in 48 patients since March 1992 to
June 1993, 22 patient;were treated withirradiation only, and the others with radiotherapy and
chemohyperthermia. In total 48 cases,39 were squamous cell carcinoma, 8 were
adenocarcinoma and one was carcino.The irradiationdose is 50-70 Gy.Hyperthermia was
performed twice a week with 60 min after each irradia-tion,using 8 MHz R F capacitive heating
equipment.The effective rate was 73.1%in radio-chemo-hyperthermia group,59.1%in irradiation
group, P>0.05. The results indicate that it ismore effective to treat synthetically advanced lung
cancer with irradiation-hyperthermia and che-motherapy,recent effection is superior to
irradiation only.
出处
《军医进修学院学报》
CAS
1995年第1期11-14,共4页
Academic Journal of Pla Postgraduate Medical School
关键词
肺肿瘤
放射疗法
药物疗法
诱导高温
lung neoplasms
radiotherapy
drug therapy
induced hyperthermia