摘要
用邻苯三酚自氧化法测定了２６例偏头痛患者发作期和间隙期红细胞超氧化物歧化酶（Ｅｒｙ－ＳＯＤ）的含量变化。结果表明，发作期和间隙期Ｅｒｙ－ＳＯＤ含量分别为１２２４±２１５Ｕ／ｇＨｂ（ｘ±ｓ）和１３２１±２０９Ｕ／ｇＨｂ，成对ｔ检验表明两者之间有非常显著差异（Ｐ＜０．００１）。偏头痛发作期Ｅｒｙ－ＳＯＤ含量显著下降，可能反映了体内氧自由基生成增加，消耗了大量的ＳＯＤ。
Levels of erythrocyte superoxide dismutase(Ery-SOD)were determined during the attack and intermittent periods in 26 patients with migraine.The results showed that the level of Ery-SOD during the attack period(1224±215U/gHb)was significantly lower than that during the intermittent period(1321±209U/gHb(paired t test, P<0.001).The decreased level of Ery-SOD suggests that the production of oxygen free radicals is increased during the attack period,which consumed a great deal of SOD.
出处
《中国疼痛医学杂志》
CAS
CSCD
1995年第2期79-81,共3页
Chinese Journal of Pain Medicine
