Ⅰ型Ⅱ型精神分裂症与神经系统软体征的关系

Neurological Soft Signs in Type Ⅰ and type Ⅱ schizophrenia

为了探讨Ⅰ型Ⅱ型精神分裂症与神经系统软体的关系，对１２０例符合中国精神疾病分类方案与诊断标准第二版精神分裂症诊断标准的病例，按Ａｒｄｒｅａｓｅｎ等的阴性、阳性精神分裂症诊断标准划分为Ⅰ型和Ⅱ型精神分裂症，（前者７６例，后者４４例），并分别进行神经系统软体征检查。结果显示，以阴性症状为主的Ⅱ型精神分裂症神经系统软体症的阳性率、平均阳性项数，平均阳性分数均较Ⅰ型精神分裂症为多，并有显著性差异，这支持以阴性症状为主的Ⅱ型精神分裂症可能代表着一种器质性病变。

A total of 120 cases fulfilling the CCMD-2 criteria of schizophrenia was collected. They were classified as type Ⅰ (76 cases) and type Ⅱ (44 cases) according to Andreasen's criteria for positive and negative symptoms.All these patients were neurologically examined for the soft signs.The results showed that the type Ⅱ schizophrenics predominantly with negative symptoms had more cases in the rate of neurological soft signs, mean positive items and mean positive seores than the type Ⅰ,The difference was markedly significant.This suggested that schizophtenia with negative symptoms might represent a variety with organic lesions.