影响成人呼吸窘迫综合征预后因素探讨

Prognostic Factors of Adult Respiratory Distress Syndrome

进行机械通气治疗的18例成人呼吸窘迫综合征（ARDS）患者，分成存活组8例和死亡组10例，作对比比较。结果发现，存活组通气24小时后的PaO2提高幅度显著大于死亡组（P＜0．05）；而通气前后PaCO2及pH值两组相比，差异不明显（P＞0．05），同时还发现存活组的并发症发生率低（62．5％），死亡组的并发症率生率高（100％）。提示观察机械通气24小时后血PaO2变化是判断ARDS预后的一个重要指标，通气24小时后PaO2迅速改善且明显，预后良好；反之预后不良；伴有并发症者预后更差。

Prognostic factors of 18 patients with adult respiratory distress syndrom (ARDS) who were given mechanical ventilation were analysed. These patients were divided into survival group (8 patients ) and death group (10 patients). After mechanical ventilation for 24 hours PaO2 level of survival group was obviously higher than that of death group,but PaCO2 and pH level of two groups were no significant difference.In addition,the complications of survival group (62. 5 % ) were less than that of death group (100 % ). These results suggested that the change of PaO2 after mechanical ventilation was a .very important index to judge of prognosis of patients with ARDS,that is,the patients whose PaO2 was improved after ventilation for 24 hours could had favourable prognosis,and if not,their outcome would be bad. Moreover, the patient with complications could had a very high mortality.