急性、亚急性重症型肠传非甲非乙型肝炎肝组织的电镜观察

Electron Microscopical Studies on Hepatic Biopsied Tissues of Acute and Subacute Severe HNANB(E)

本文报告5例急性重症型和1例亚急性重症型肠道传播的非甲非乙型肝炎病人肝穿活检标本的电镜观察结果。5例急性重症型肝炎中3例死亡,2例恢复。死亡病人的肝细胞以溶解性和嗜酸性坏死表现为主,而恢复期的病人肝细胞内各种细胞器只残留轻微的变性改变。亚急性重症型肝炎病人的肝细胞以嗜酸性变为主,Disse间隙及肝窦内淤胆明显。

Liver biopsied specimens were obtained from 5 cases with acute severe HNANB(E) patients (3 died and 2 recovered), and one subacute severe HNANB(E) patient(died). These specimens were observed with electron microscope. Results showed that in the three dead patients of acute severe HNANB(E), the dissolved and acidophile necrosis were mainly manifested in hepatic cells; in the two recovered patients, slight degenerative change of organelles were remained in hepatic cells; in the patient of subacute severe HNANB(E), the acidophile degeneration was seen chiefly in the hepatic cells and obvious bile stasis in Disse spaces and sinusoids.