576个椎体孤立性微骨痂形成的病理研究

Pathological research on isolated microcallus formation in 576 vertebrae

从２４例尸体解剖所得完整的脊柱标本共５７６个椎体，检查了微骨痂的存在、数量及分布，描述了它的组织学特点，初步探讨了它的发病机理。组成微骨痂的细胞来源于骨小梁表面的骨母细胞及邻近的骨髓网织细胞，早期为幼稚的波纹骨，以后演变为成熟的板层骨。微骨痂的形成与所受应力有关，受力越大微骨痂数量越多，腰椎是微骨痂形成最多的部位。微骨痂的形成与年龄有关，微骨痂数量在５０岁以后有随着年龄增加而增多的趋势，可能与不同程度的骨质疏松有关。

76 vertebrae specimens obtained from 24 autopsy cases were studied for microcallus.Microcallus consisted of osteocytes which originated from osteoblasts located on the surface of tra-beculae and from medullary reticulum cells. In the early stage,microcallus is immature woven bonewhichlater transforms into mature lamellar bone.The incidence of microcallus is related to stress on thevertebral body and to the age of the patient,therefore, most microcallus were found in the lumbar verte-brae and in the elderly.