MPTCP和PTCP陶瓷治疗兔骨缺损的对比研究

Comparison of the Treatment with MPTCPand PTCP Ceramics Implanted in the Surgical De-fects in Rabbits

为探讨磁性多孔磷酸三钙陶瓷（ＭＰＴＣＰ）治疗骨缺损的实用价值，将ＭＰＴＣＰ和多孔磷酸三钙陶瓷（ＰＴＣＰ）分别植入兔左、石桡骨中段骨缺损内，通过肉眼观查、光学及电子显微镜、Ｘ线检查、新骨形成面积定量分析、抗折试验等５个月实验表明，ＭＰＴＣＰ及ＰＴＣＰ陶瓷均具有良好的生物相容性。在早期（１～３个月），ＭＰＴＣＰ陶瓷较之ＰＴＣＰ陶瓷能引起更多的新骨形成。

AbstractThe magnetic porous tricalcium phosphate(MPTCP)and porous tricalcium phosphate(PTCP)ceramic cylinders were implanted in rightand left bony defects of rabbits’radii in order todetermine the utility of the MPTCP ceramics. Through naked eye inspection,light and scanningelectron microphotography,roentgenography,quantitative histological measurement of new boneformation and anti-break test in the period of 5months,both ceramics were proved to be biocom-patible. MPTCP ceramics could induce more newbone formation than did the PTCP ceramics.