胆脂瘤和外耳道上皮的黑色素细胞

Presence of melanocytes in the epithelium of the external ear canal and the cholesteatoma

本文用组织化学和免疫组化等方法，研究２６例后天性胆脂瘤标本中的黑色素细胞，查见８例（３０．８％）胆脂瘤有黑色素细胞。用同法研究２例胎儿及１例死婴的外耳及中耳，见外耳道和鼓膜的表皮有黑色素细胞，而中耳粘膜则无。因此认为，那些无黑色素细胞的胆脂瘤上皮可来源于中耳粘膜的鳞状化生。

Abstract The melanocytes were investigated histochemically and immunohistochemically on theepithelia of 26 cholesteatomas and the epithelia of external and middle ear of two fetuses andone newborn。 Eight of twenty-six cholesteatomas(30.8%)revealed melanocytes and eigh-teen specimens no melanocytes.Melanocytes demonstrated in the epidermis of external earcanal and tympanic membrane,but no melanocyte was found in the middle ear mucous ep-itheliu m。The results showed that the cholesteatoma epithelia without melanocyte mightoriginate from squamous metaplasia of middle ear mucosa。