胃癌浸润深度与原发瘤部位和淋巴结转移的关系

Relation of the Invasive Depth between the Location of Carcinoma and the Metastasis of Lymph Nodes

通过１３１例胃癌的原发部位、组织学类型、浸润深度和淋巴结转移的关系的分析，发现胃各部位的早期癌比中晚期癌均有较低的淋巴结转移发生率；中晚期癌多见于胃底贲门部，早期癌多见于胃窦幽门部，两期癌的部位分布差异有非常显著性意义（Ｐ＜０．０１）；两期癌的组织学类型差异在各个部位无显著性，均以肠型胃癌为多，表明胃癌的浸润深度与原发部位关系明显，与组织学类型关系不明显。这可能由于发生在胃底贲门部的癌早期症状隐匿，该部位是Ｘ线或胃镜检查观察的困难部位，早期癌比较难发现。

Statistical anaysis showed that the primary site of gastric carcinoma of 131 cases were associated with their invasive depth, histological type and lymphatic metastasis. It was found that the incidences of lymphatic node metastasis of early cancer (PT1) were located at any region of stomach which was lower than that of the advanced cancer(PT2). The PT1 tumor frequently occurred in the pyloric antrum and the PT2 tumor mostly in the fundus ventriculi or cardia. Statistically there were district difference (P<0.01) in the locational distribution but not in histological type. The intestinal type of gastric carcinoma was the most frequent in both PT1 and PT2 cancer. This suggested that the invasive depth of the tumor was closely related to the location of the original tumor but not related to histological type. The PT2 tumor occurred more frequently in the fundus ventriculi or cardia because where was very difficult for an early x-ray or gastroscopic examination and the symptom of that tumor might be obscure or even symptomless.