摘要
应用毛细管柱气相色谱法分析比较了１５例大肠癌患者癌组织与癌周围正常组织脂肪酸组成情况。结果显示，癌组织磷脂的Ｃ１６：０、Ｃ１８：０和Ｃ１８：０／Ｃ１８：１比值（ＳＩ值）降低，Ｃ２０：４和不饱和脂肪酸／饱和脂肪酸比值升高，但中性脂肪酸组成无明显改变。提示，脂肪酸在组织中分布的差异可能与肿瘤的发生发展有关。
The Fatty acid composition of phospholipids and neutral lipids in
cancer tissues and non─cancerous tissues in 15 patients with cancer
of large intestine were analysed by capillary─column gas─liquid
chromatography(GLC). Results showed a significant reduction in C16:0,
C18:0 and C18:0/C18:1 (SI), and a significant enhancement in C20 :4
and unsaturated fatty acids/saturated fatty acids molar ratios ( U/S)
in phospholipids were observed in cancer tissues as compared to
noncancerous tissues in patients with cancers of large intestine.
However the fatty acid composition of neutreul lipids were similar in
cancer tissues as compared to non─cancerous tissues.It was suggested
that abnormalities of fatty acid distribution in the tissue
phospholipids of patient with cancer could be related to tumour
growth.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1995年第5期340-342,共3页
Chinese Journal of Cancer
关键词
大肠肿瘤
脂肪酸
气相色谱法
Neoplassma Fatty acids Gas chromatography
