摘要
本实验观察了不同剂量（０、５０、７５、１５０ｍＧｙ和２、４Ｇｙ）Ｘ线单次全身照射昆明系小鼠后腹腔巨噬细胞（Ｍ）对鸡红细胞（ＣＲＢＣ）吞噬消化功能的影响。其结果表明，５０和７５ｍＧｙ照射后３和５天Ｍ对ＣＲＢＣ的吞噬功能明显增加（Ｐ＜０．００１），７５ｍＧｙ照射后Ｍ消化功能更为显著（Ｐ＜０．０１），而２和４Ｇｙ照射后其吞噬和消化功能降低。提示，低剂量辐射能够刺激机体非特异性免疫功能，大剂量照射使之受抑制。
This study was undertaken to observe
the effects of single whole body irradiationwith 0,0.05,0.075,0.15,2. 0 and 4.0 Gy X-rays on the
functions of peritoneal macrophages in en-gulfing and digesting the red blood cells of
chiken(CRBC)in Kunming mice. The results showed thatthe functions of macrophages in
engulfing CRBC increased obviously 3 and 5 days after the irradiationwith 0.05 and 0.075
Gy,and their digestive functions were significantly higher than in 0 Gy groupafter the irradiation
with 0.075 Gv. Howeve, their engulfing and digesting ftinctions decreased afterthe irradiation
with 2 and 4 Gy. These suggest that low dose radiation can stimulate the function ofnonspecific
immunity,while large dose radiation can inhibite it.
出处
《白求恩医科大学学报》
CSCD
1995年第4期331-332,共2页
Journal of Norman Bethune University of Medical Science
基金
国家自然科学基金
