核桃仁对大鼠体内外脂质过氧化的影响

EFFECT OF WALNUT ON LIP1D PEROXIDATION IN VIVO AND IN VITRO OF RAT

本文观察了不同年龄大鼠体内脂质过氧化物（ＬＰＯ）及红细胞超氧化物歧化酶（ＳＯＤ）含量。结果显示：大鼠随年龄增长，血浆及肝、脑组织中ＬＰＯ含量升高。红细胞中ＳＯＤ活性下降。但喂饲核桃仁３个月后的老龄大鼠与对照组相比，ＬＰＯ含量下降（Ｐ＜０．０５），ＳＯＤ活性增高（Ｐ＜０．０５），肝、脑组织匀浆体外培养，加核桃仁试管中的ＬＰＯ明显低于对照组（Ｐ＜０．０１），提示核桃仁确有一定的抗氧化作用．

The level of plasma and brain lipid peroxide in old rats increased and activity of su-peroxide dismutase reduced.The level of lipid peroxide in old rats by oral administration of wal- nut l0g/kg perday for three months was lower than that of the control group(p<0.05).Theactivity of superoxide dismutase was higher than that of the control group(P<O.05).The re-sults showed that walnut had antagonistic effects on lipid peroxidation。