大鼠运动性动情周期抑制时hcG对卵巢内分泌的影响

Effects of Human Chorionic Gonadotropin on Ovarian Internal Secretion in Rats during the Inhibiting Exercise Estrous Cycle

为从卵巢水平探讨运动性闭经的机制，选择动情周期正常的纯系雌性大鼠为实验对象，以大负荷游泳训练建立运动性动情周期抑制的动物模型。通过卵巢对人绒毛膜促性腺激素（hcG）兴奋试验，测定运动性动情周期抑制时卵巢中孕酮的变化。结果表明，卵巢对外源性促性腺激素hcG仍有敏感的反应，促进孕酮（P）的释放增加，提示卵巢分泌P的功能未发生不可逆的改变。

To approach the mechanism of exercise amenorrhoea at the ovarian level normal purebred female rats in estrous cycle were chosen as the subjects of the experiment. The animal model of inhibiting exercise estrous cycle was established by heavy load swimming training. The change of progesterone in ovaries during the inhibiting exercise estrous cycle was determined by exciting human chorionic gonadotropin experiment. The results showed that ovaries still had their sensitive reactions to the exogenous chorionic gonadotropin and promoted the release of progesterone. It was pointed out that unreversible changes had not occurred in the ovarian function to secrete progesterone.