摘要
用放射免疫法测定２０４例糖尿病人的血浆ＴＸＢ２和６－Ｋｅｔｏ－ＰＧＦ１ａ浓度。各组的ＴＸＢ２水平，随糖尿病视网膜病变或糖尿病肾病加重而升高。各糖尿病微血管病变组中高血压组ＴＸＢ２水平均高于血压正常组（Ｐ＜０．０５）。提示ＴＸＢ２在糖尿病微血栓形成中起重要作用，合并高血压时对糖尿病微血管病变的发生和进展有明显的促进作用。
e measured plasma thromboxane B2
and 6-keto-prostaglandin F1ausing radioimmunoassay in 204 diabetic
pa-tients. The results showed that the TXB2 level was significantly
higher in diabetic retinopathy or diabetic nephropathy groups than
that in normal subjects(P<0. 01 ).The TXB2 level in hypertensive
diabetic patients from each of the above groups was significantly
higher than those of normotensive patients in the same group(P<
0.05).Our results suggest that thromboxane B2 may involve in the
pathogenesis of microangiopathy in diabetesmellitus and hypertension
may play a role in the progression of diabetic microangiopathy.
出处
《北京医科大学学报》
CSCD
1995年第5期367-369,共3页
Journal of Peking University(Health Sciences)
关键词
糖尿病
微血管病变
并发症
高血压
血栓素
Headings Diabetes mellitus/complication
Hypertension
Thromboxane B2/analysis
