摘要
报告结扎一侧颈总动脉、部分阻断基底动脉所造成的椎基底动脉脑缺血动物模型。血管阻断后基底动脉内血细胞流动减少、血流变慢；脑干电图示波幅减低、频率减低；脑干听诱发电位出现反应阈增高、潜伏期延长和波幅减低；耳蜗血流减低４７．４１ＡＢＬ％。证明这是一个研究椎基底动脉供血障碍基础和临床的实用、有效和符合临床特点的动物模型。
his is the
first report on an animal model of VBI.The severity of ischemia was
established by brainstem elec-troencephalogram,ABR and laser Doppler
flowmetry etc.When these vessels were obstrticted,all of them have
been obviously changed.It is proved to be a useful and effective
animal model,conforming to the clinical character-istics.In
conseqence,this model is particularly suited for basic or clinical
experiments of VBI and inner ear.
出处
《北京医科大学学报》
CSCD
1995年第6期427-429,共3页
Journal of Peking University(Health Sciences)
基金
卫生部科研基金
关键词
脑缺血
椎底动脉
供血不足
动物模型
Headings Vertebrobasilar
insufficiency
Disease models,animal
