新生儿窒息时部分生化指标改变的分析

An analysis of the change of partial biochemical index in the neonatal asphyxia

选择新生儿窒息者４１例，与正常新生儿比较，ＡＬＴ、ＡＳＴ、ＢＵＮ、α－ＨＢＤＨ、ＣＰＫ、ＬＤＨ及ＣＲＥＡ均值均有显著性差异。按窒息时间长短分成三组。对照组与窒息时间小于５分组相比较，ＡＳＴ、α－ＨＢＤＨ、ＣＰＫ、ＬＤＨ及ＣＲＥＡ两组均数间有显著性差异；对照组与窒息时间５～１０分组相比较，ＡＳＴ、ＢＵＮ、α－ＨＢＤＨ、ＣＰＫ、ＬＤＨ及ＣＲＥＡ两组均数间有显著性差异；窒息时间小于５分组与５～１０分组相比较，只有ＬＤＨ两组均数间有显著性差异；窒息时间５～１０分组与大于１０分组相比较，ＡＬＴ、ＡＳＴ及ＣＲＥＡ两组均数间有显著性差异；对照组、窒息时间小于５分组分别与窒息时间大于１０分组相比较，上述生化指标均数间均有显著性差异。

A number of blood biochemical contents of 41 neonatal asphyxia were studied in patients.Comparison with those of normal newborn infants. The results revealed that the mean values of ALT, AST, BUN,α-HBDH, CPK, LDH and CREA of these 2 types of infants are significantly different. The patients were divided into three groups according to the time of asphyxia and the normal newborn as control. The mean values of AST,α-HBDH, CPK, LDH and CREA showed significant differences between control group and the patient of asphyxia below 5 minutes. The mean values of AST, BUN,α-HBDH, CPK, LDH and CREA had significant difference between controls and the patient s with time of asphyxia 5 to 10 minutes, too. Only the mean value of LDH had showed significant difference between the infants of asphyxia below 5 minutes and those from 5 to 10 minutes. The mean value of ALT, AST, and CREA had significant differences between the infants of asphyxia for 5 to 10 minutes and those above 10 minutes, The mean values of all above-mentioned biochemical indices had revealed significant differences among the 3 groups.