烧伤病人输血后丙肝发生情况报告

The detection of anti-HCV and HCV-RNA in burn patients after transfusion

采用酶联免疫反应（ＥＬＩＳＡ）及聚合酶链反应（ＰＣＲ）方法，对２０例烧伤病人血清丙型肝炎病毒抗体（抗ＨＣＶ）及丙型肝炎病毒（ＨＣＶ）ＲＮＡ进行了检测。结果：入院时，输血组及非输血组挤－ＨＣＶ及ＨＣＶＲＮＡ检测均为阴性。一个月后，输血组１０例病人中发现抗－ＨＣＶ阳性５例、ＨＣＶ ＲＮＡ阳性４例；而非输血组抗－ＨＣＶ及ＨＣＶＲＮＡ检测均为阴性。说明输血是烧伤病人感染ＨＣＶ的重要途径。本文还对烧伤病人输血后抗－ＨＣＶ及ＨＣＶ ＲＮＡ阳性率高的原因进行了分析。

Hepatitis C virus antibody (anti-HCV) and HCV-RNA were detected in t he sera of 20 burn patients with method of ELISA and polymerase chain reaction(PCR).The results showed that anti-HCV and HCV-RNA were negative in both transfusion group and non-transfusion group,on admission. One month later, anti-HCV was positive in 5 of the l0 patients and HCV-RNA in 4 of the 10 patients in the transfusion group. Both anti-HCV and HCV-RNA were negative in the nontransfusion group. The results suggest that transfusion is an important route for the HCV infection in burn patients. The causes of high positive rate of anti-HCV and HCV-RNA in the burn patients after transfusion were analysed.